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KMID : 0032220170290040487
Annals of Dermatology
2017 Volume.29 No. 4 p.487 ~ p.490
Lobulated Bowen's Disease with a Clear Cell Change
Lee Dong-Yoon

Choi Ki-Hwa
Park Su-Hyun
Lee Ji-Yeoun
Yoon Tae-Young
Abstract
Bowen's disease usually manifests as a slowly enlarging erythematous scaly patch or plaque. An uncommon variant of Bowen's disease showing a verrucous appearance has been reported and a distinct variant with a prominent clear cell change on histopathology, in addition to a verrucous surface change, was also reported. We describe novel form of Bowen's disease having a cerebriform appearance and showing histopathologically a significant clear cell change and propose that the clinical term ¡°lobulated Bowen's disease¡± would be compatible for the description of this unique clinical variant. From a histopathological point of view, the precise definition and etiopathogenesis of the clear cell change in Bowen's disease should be elucidated.
KEYWORD
Bowen's disease, Clear cell, Lobulated
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